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url url url url
  2. Weltenzyklopädie
  3. فنوتیازین - ویکی‌پدیا، دانشنامهٔ آزاد
فنوتیازین - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
Phenothiazine
نام‌گذاری آیوپاک

10H-phenothiazine

دیگر نام‌ها

thiodiphenylamine dibenzothiazine dibenzoparathiazine 10H-dibenzo-[b'e]-14-thiazine PTZ

شناساگرها
شماره ثبت سی‌ای‌اس 92-84-2 ✔Y
کم‌اسپایدر 21106365 ✔Y
UNII GS9EX7QNU6 ✔Y
KEGG D02601 ✔Y
ChEBI CHEBI:37931 N
ChEMBL CHEMBL828 ✔Y
جی‌مول-تصاویر سه بعدی Image 1

  • c1ccc2c(c1)Nc3ccccc3S2

  • InChI=1S/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H ✔Y
    Key: WJFKNYWRSNBZNX-UHFFFAOYSA-N ✔Y

    InChI=1/C12H9NS/c1-3-7-11-9(5-1)13-10-6-2-4-8-12(10)14-11/h1-8,13H
    Key: WJFKNYWRSNBZNX-UHFFFAOYAI

خصوصیات
فرمول مولکولی C12H9NS
جرم مولی 199.27 g/mol
شکل ظاهری yellow rhombic leaflets or

diamond-shaped plates

دمای ذوب ۱۸۵ درجه سلسیوس (۳۶۵ درجه فارنهایت؛ ۴۵۸ کلوین)
دمای جوش ۳۷۱ درجه سلسیوس (۷۰۰ درجه فارنهایت؛ ۶۴۴ کلوین)
انحلال‌پذیری در آب 0.00051 g/L (20 °C)[۱]
انحلال‌پذیری در other solvents بنزن دی‌اتیل اتر petroleum ether کلروفرم hot استیک اسید اتانول (slightly) mineral oil (slightly)
اسیدی (pKa) approx 23 in DMSO
به استثنای جایی که اشاره شده‌است در غیر این صورت، داده‌ها برای مواد به وضعیت استانداردشان داده شده‌اند (در 25 °C (۷۷ °F)، ۱۰۰ kPa)
 N (بررسی) (چیست: ✔Y/N؟)
Infobox references

فنوتیازین (به انگلیسی: Phenothiazine) با فرمول شیمیایی C۱۲H۹NS یک ترکیب شیمیایی است. که جرم مولی آن ۱۹۹٫۲۷ g/mol می‌باشد. این ترکیب شیمیایی بعنوان یک داروی ضد روانپریشی نسل اول قدرتمند سالهاست که با نام تجاری اصیل لارگاکتیل ساخته شده و دهه هاست مورد تحقیقات گسترده‌ای نیز قرار گرفته است. این دارو ده برابر از اولین داروی آنتی سایکوتیک یعنی کلرپرومازین قوی تر است.(میل به انسداد گیرنده D2 دوپامینی دارد.)

جستارهای وابسته

منابع

  1. ↑ Sigma-Aldrich catalog
  • «IUPAC GOLD BOOK». دریافت‌شده در ۱۸ مارس ۲۰۱۲.


آیکون خرد

این یک مقالهٔ خرد شیمی است. می‌توانید با گسترش آن به ویکی‌پدیا کمک کنید.

Pusat Layanan

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