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url url
  2. Weltenzyklopädie
  3. پیترازپین
پیترازپین
از ویکی‌پدیا، دانشنامهٔ آزاد
پیترازپین
داده‌های بالینی
رده‌بندی داروهای
بارداری
  • ?
روش مصرف دارو?
کد ATC
  • None
وضعیت قانونی
وضعیت قانونی
  • Uncontrolled
شناسه‌ها
  • 3-(piperazin-1-yl)-9H-dibenzo[c,f][1,2,4]triazolo[4,3-a]azepine
شمارهٔ سی‌ای‌اس
پاب‌کم CID
کم‌اسپایدر
UNII
CompTox Dashboard (EPA)
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC19H19N۵
جرم مولی۳۱۷٫۳۹۶ g·mol−1
مدل سه بعدی (جی‌مول)
  • n4nc(N1CCNCC1)n5c2ccccc2Cc3ccccc3c45

پیترازپین (به انگلیسی: Pitrazepin) یک آنتاگونیست رقابتی GABAA و گیرنده گلیسین است.[۱][۲][۳] از این ماده برای مطالعه دستگاه عصبی حشرات و حلزون در تحقیقات علمی استفاده شده‌است.[۴][۵][۶][۷][۸][۹]

همچنین ببینید

[ویرایش]

منابع

[ویرایش]
  1. ↑ Gähwiler BH, Maurer R, Wüthrich HJ (April 1984). "Pitrazepin, a novel GABAA antagonist". Neuroscience Letters. 45 (3): 311–6. doi:10.1016/0304-3940(84)90244-1. PMID 6328380.
  2. ↑ Braestrup C, Nielsen M (November 1985). "Interaction of pitrazepin with the GABA/benzodiazepine receptor complex and with glycine receptors". European Journal of Pharmacology. 118 (1–2): 115–21. doi:10.1016/0014-2999(85)90669-7. PMID 3002806.
  3. ↑ Curtis DR, Gynther BD (November 1986). "Pitrazepin: a central glycine and GABA antagonist". European Journal of Pharmacology. 131 (2–3): 311–3. doi:10.1016/0014-2999(86)90590-X. PMID 3816960.
  4. ↑ Anthony NM, Harrison JB, Sattelle DB (1993). "GABA receptor molecules of insects". Exs. 63: 172–209. doi:10.1007/978-3-0348-7265-2_8. ISBN 978-3-0348-7267-6. PMID 7678525.
  5. ↑ Sattelle DB, Pinnock RD, Wafford KA, David JA (January 1988). "GABA receptors on the cell-body membrane of an identified insect motor neuron". Proceedings of the Royal Society B. 232 (1269): 443–56. Bibcode:1988RSPSB.232..443S. doi:10.1098/rspb.1988.0006. PMID 2451252.
  6. ↑ Murphy VF, Wann KT (November 1988). "The action of GABA receptor agonists and antagonists on muscle membrane conductance in Schistocerca gregaria". British Journal of Pharmacology. 95 (3): 713–22. doi:10.1111/j.1476-5381.1988.tb11697.x. PMC 1854212. PMID 2850061.
  7. ↑ Zhang W, Han XY, Wong SM, Takeuchi H (January 1997). "Pharmacologic characteristics of excitatory gamma-amino-butyric acid (GABA) receptors in a snail neuron". General Pharmacology. 28 (1): 45–53. doi:10.1016/S0306-3623(96)00152-8. PMID 9112076.
  8. ↑ Kim KH, Takeuchi H (June 1990). "Pharmacological characteristics of two different types of inhibitory GABA receptors on Achatina fulica neurones". European Journal of Pharmacology. 182 (1): 49–62. doi:10.1016/0014-2999(90)90492-O. PMID 2169426.
  9. ↑ Takeuchi H (September 1992). "Sensitivities of Achatina giant neurones to putative amino acid neurotransmitters". Comparative Biochemistry and Physiology C. 103 (1): 1–12. doi:10.1016/0742-8413(92)90219-w. PMID 1360362.
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