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url url url url
  2. Weltenzyklopädie
  3. فلوکلوتیزولام - ویکی‌پدیا، دانشنامهٔ آزاد
فلوکلوتیزولام - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
فلوکلوتیزولام
وضعیت قانونی
وضعیت قانونی
شناسه‌ها
  • 2-chloro-4-(2-fluorophenyl)-9-methyl-4H-thieno[3,2-f] [1,2,4]triazolo[4,3-a] [1,4]diazepine
شمارهٔ سی‌ای‌اس
پاب‌کم CID
کم‌اسپایدر
UNII
CompTox Dashboard (EPA)
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC15H10ClFN4S
جرم مولی۳۳۲٫۷۸ g·mol−1
مدل سه بعدی (جی‌مول)
  • Fc4ccccc4C2=NCc1nnc(C)n1c3sc(Cl)cc23
  • InChI=1S/C15H10ClFN4S/c1-8-19-20-13-7-18-14(9-4-2-3-5-11(9)17)10-6-12(16)22-15(10)21(8)13/h2-6H,7H2,1H3
  • Key:ZDYRCUZZLRLMHG-UHFFFAOYSA-N

فلوکلوتیزولام (انگلیسی: Fluclotizolam) یک مشتق تینوتریازولودیازپین است که برای نخستین بار در سال ۱۹۷۹ میلادی سنتز شد،[۱] اما هرگز به بازار عرضه نشد. متعاقباً به عنوان یک داروی طراح فروخته شد و نخستین بار در سال ۲۰۱۷ به طور قطعی شناسایی شد.[۲][۳][۴][۵][۶][۷]

جستارهای وابسته

منابع

  1. ↑ US 4155913, Hellerbach J, Zeller P, Binder D, Hromatka O, "Thienotriazolodiazepine derivatives.", issued 22 May 1979, assigned to Hoffmann La Roche Inc 
  2. ↑ Zawilska JB, Wojcieszak J (July 2019). "An expanding world of new psychoactive substances-designer benzodiazepines". Neurotoxicology. 73: 8–16. doi:10.1016/j.neuro.2019.02.015. PMID 30802466. S2CID 73461430.
  3. ↑ Moosmann B, Auwärter V (2018). "Designer Benzodiazepines: Another Class of New Psychoactive Substances.". In Maurer H, Brandt S (eds.). New Psychoactive Substances. Handbook of Experimental Pharmacology. Handbook of Experimental Pharmacology. Vol. 252. pp. 383–410. doi:10.1007/164_2018_154. ISBN 978-3-030-10560-0. PMID 30367253.
  4. ↑ Chetraru E, Ameline A, Gheddar L, Raul JS, Kintz P (February 2018). "Les designer benzodiazepines: qu'en sait-on aujourd'hui?". Toxicologie Analytique et Clinique. 30 (1): 5–18. doi:10.1016/j.toxac.2017.12.001.
  5. ↑ Orsolini L, Corkery JM, Chiappini S, Guirguis A, Vento A, De Berardis D, Papanti D, Schifano F (2020). "'New/Designer Benzodiazepines': An Analysis of the Literature and Psychonauts' Trip Reports". Current Neuropharmacology. 18 (9): 809–837. doi:10.2174/1570159X18666200110121333. PMC 7569319. PMID 31933443.
  6. ↑ Catalani V, Botha M, Corkery JM, Guirguis A, Vento A, Scherbaum N, Schifano F (July 2021). "The Psychonauts' Benzodiazepines; Quantitative Structure-Activity Relationship (QSAR) Analysis and Docking Prediction of Their Biological Activity". Pharmaceuticals. Basel, Switzerland. 14 (8): 720. doi:10.3390/ph14080720. PMC 8398354. PMID 34451817.
  7. ↑ Catalani, Valeria; Floresta, Giuseppe; Botha, Michelle; Corkery, John Martin; Guirguis, Amira; Vento, Alessandro; Abbate, Vincenzo; Schifano, Fabrizio (July 2022). "In silico studies on recreational drugs: 3D‐QSAR prediction of classified and de novo designer benzodiazepines". Chemical Biology & Drug Design. 101 (1): 40–51. doi:10.1111/cbdd.14119. ISSN 1747-0277. PMID 35838189. S2CID 250559695.

پیوند به بیرون

در ویکی‌انبار پرونده‌هایی دربارهٔ فلوکلوتیزولام موجود است.
آیکون خرد

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