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url url url url
  2. Weltenzyklopädie
  3. تیئنوتری‌آزولودیازپین - ویکی‌پدیا، دانشنامهٔ آزاد
تیئنوتری‌آزولودیازپین - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
ساختار اصلی تینوتری‌آزولودیازپین ها

تیئنوتری‌آزولودیازپین [۱] یک ترکیب هتروسیکلیک حاوی یک حلقه دیازپین با حلقه های تیوفن و تریازول متصل شده است. تیانوتریازولودیازپین هسته اصلی چندین داروی شیمیایی را تشکیل می دهد از جمله:

تینوتری‌آزولودیازپین‌ها با سایت گیرنده بنزودیازپین تعامل می کنند، آن‌ها معمولاً اثرات مشابه 4،1-بنزودیازپین ها (مانند دیازپام) و تری‌آزولوبنزودیازپین ها (مانند آلپرازولام) دارند.

تینوتری‌آزولودیازپین ها که GABAA receptor positive allosteric modulator نیستند عبارتند از:

منابع

  1. ↑ Catabay, A.; Taniguchi, M.; Jinno, K.; Pesek, J. J.; Williamsen, E. (1 March 1998). "Separation of 1,4-Benzodiazepines and Analogues Using Cholesteryl-10-Undecenoate Bonded Phase in Microcolumn Liquid Chromatography". Journal of Chromatographic Science. 36 (3): 113. doi:10.1093/chromsci/36.3.111.
  2. ↑ Hirota, N; Yasuda, D; Hashidate, T; Yamamoto, T; Yamaguchi, S; Nagamune, T; Nagase, T; Shimizu, T; Nakamura, M (Feb 2010). "Amino acid residues critical for endoplasmic reticulum export and trafficking of platelet-activating factor receptor". Journal of Biological Chemistry. 285 (8): 5931–40. doi:10.1074/jbc.M109.066282. PMC 2820818. PMID 20007715.
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