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url url url url
  2. Weltenzyklopädie
  3. فلوآلپرازولام - ویکی‌پدیا، دانشنامهٔ آزاد
فلوآلپرازولام - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
فلوآلپرازولام
وضعیت قانونی
وضعیت قانونی
شناسه‌ها
  • 8-chloro-6-(2-fluorophenyl)-1-methyl-4H-benzo[f] [1,2,4]triazolo[4,3-a] [1,4]diazepine
شمارهٔ سی‌ای‌اس
پاب‌کم CID
کم‌اسپایدر
UNII
CompTox Dashboard (EPA)
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC17H12ClFN4
جرم مولی۳۲۶٫۷۶ g·mol−1
مدل سه بعدی (جی‌مول)
  • CC1=NN=C2N1C3=C(C=C(C=C3)Cl)C(=NC2)C4=CC=CC=C4F
  • InChI=1S/C17H12ClFN4/c1-10-21-22-16-9-20-17(12-4-2-3-5-14(12)19)13-8-11(18)6-7-15(13)23(10)16/h2-8H,9H2,1H3
  • Key:MPZVLJCMGPYWQQ-UHFFFAOYSA-N

فلوآلپرازولام (انگلیسی: Flualprazolam) یک آرام‌بخش از دسته تریازولوبنزودیازپین‌ها (TBZD) است که بنزودیازپین‌ها (BZD) هستند که با یک حلقه تری‌آزول ترکیب شده‌اند.[۲] این دارو نخستین بار در سال ۱۹۷۶ سنتز شد، اما هرگز به بازار عرضه نشد. می‌توان آن را به عنوان نسخه تری آزولو فلودیازپام دید. این ماده دارای اثر آرام‌بخش است.[۳][۴][۵][۶]

جستارهای وابسته

منابع

  1. ↑ "(Proposed Rule) Schedules of Controlled Substances: Temporary Placement of Etizolam, Flualprazolam, Clonazolam, Flubromazolam, and Diclazepam in Schedule I". Drug Enforcement Administration. December 23, 2022.
  2. ↑ US 3987052, Hester JB, et al., "6-Phenyl-4H-s-triazolo[4,3-a][1,4]benzodiazepines." 
  3. ↑ Wagmann L, Manier SK, Bambauer TP, Felske C, Eckstein N, Flockerzi V, Meyer MR (February 2020). "Toxicokinetics and analytical toxicology of flualprazolam: metabolic fate, isozyme mapping, human plasma concentration, and main urinary excretion products". Journal of Analytical Toxicology. 44 (6): 549–558. doi:10.1093/jat/bkaa019. PMID 32104896.
  4. ↑ Papsun, Donna M.; Krotulski, Alex J.; Homan, Joe; Temporal, Keith D. H.; Logan, Barry K. (June 2020). "Flualprazolam Blood Concentrations in 197 Forensic Investigation Cases". Journal of Analytical Toxicology. 45 (3): 226–232. doi:10.1093/jat/bkaa070. PMID 32542312.
  5. ↑ Rice, Kathleen; Hikin, Laura; Lawson, Alexander; Smith, Paul R.; Morley, Stephen (August 2020). "Quantification of Flualprazolam in Blood by LC–MS-MS: A Case Series of Nine Deaths". Journal of Analytical Toxicology. 45 (4): 410–416. doi:10.1093/jat/bkaa098. PMID 32780842.
  6. ↑ Ling, Jiang; Zhang, Wenqi; Yan, Xiaojun; Liu, Wenlong; Wang, Yanyan; Ding, Yanjun (August 2022). "Sensitive detection and primary metabolism analysis of flualprazolam in blood". Journal of Forensic and Legal Medicine. 90: 102388. doi:10.1016/j.jflm.2022.102388. ISSN 1752-928X. PMID 35691207.
آیکون خرد

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