Lifestyle Khazanah Profil Baru Dram Lists Ensiklopedia
Technopedia Center
PMB University Brochure
Faculty of Engineering and Computer Science
S1 Informatics S1 Information Systems S1 Information Technology S1 Computer Engineering S1 Electrical Engineering S1 Civil Engineering

faculty of Economics and Business
S1 Management S1 Accountancy

Faculty of Letters and Educational Sciences
S1 English literature S1 English language education S1 Mathematics education S1 Sports Education
teknopedia

teknopedia

teknopedia

teknopedia

teknopedia

teknopedia
teknopedia
teknopedia
teknopedia
teknopedia
teknopedia
url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url 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url url
  2. Weltenzyklopädie
  3. اپروبماید
اپروبماید
از ویکی‌پدیا، دانشنامهٔ آزاد
اپروبماید
داده‌های بالینی
نام‌های تجاریBefol (روسیه)
نام‌های دیگرBefol
روش مصرف داروخوراکی
وضعیت قانونی
وضعیت قانونی
  • ℞ (Prescription only)
شناسه‌ها
  • 4-Chloro-N-[3-(4-morpholinyl)propyl]benzamide
شمارهٔ سی‌ای‌اس
پاب‌کم CID
کم‌اسپایدر
UNII
ChEMBL
CompTox Dashboard (EPA)
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC14H19ClN2O2
جرم مولی۲۸۲٫۷۷ g·mol−1
مدل سه بعدی (جی‌مول)
  • C1COCCN1CCCNC(=O)C2=CC=C(C=C2)Cl
  • InChI=1S/C14H19ClN2O2/c15-13-4-2-12(3-5-13)14(18)16-6-1-7-17-8-10-19-11-9-17/h2-5H,1,6-11H2,(H,16,18)
  • Key:YYFGRAGNYHYWEZ-UHFFFAOYSA-N

اپروبماید(به انگلیسی: Eprobemide) (INN) دارویی است که به عنوان ضد افسردگی در روسیه (با نام تجاری Бефол/Befol) استفاده می‌شد.[۱] این ماده یک بازدارنده غیر رقابتی برگشت‌پذیر مونوآمین اکسیداز A است[۲][۳] که در مورد آمین‌زدایی سروتونین عملکرد انتخابی از خود نشان می‌دهد.[۴] تفاوت اپروبماید و مکلوبماید فقط در اتصال دهنده‌ای است که قطعه مورفولین را به کلروبنزامید متصل می‌کند. موکلوبماید دارای دو اتم کربن است در حالی که اپروبماید سه اتم کربن دارد. ثبت تجاری ای ن دار در ۳۰ دسامبر ۲۰۰۳ لغو شد.[۵]

منابع

[ویرایش]
  1. ↑ Ganellin CR, Triggle DJ (1996). Dictionary of Pharmacological Agents. Vol. 3. p. 811. ISBN 978-0412466304.
  2. ↑ Gol'dina OA, Moskvitina TA, Gankina EM, Kirkel' AZ, Kamyshanskaia NS, Lopatina KI, et al. (March 1991). "[The action of befol and its derivatives on monoamine oxidase of different origins]". Biulleten' Eksperimental'noi Biologii I Meditsiny. 111 (3): 279–80. PMID 2054504.
  3. ↑ Donskaya NS, Antonkina OA, Glukhan EN, Smirnov SK (2004-07-01). "Antidepressant Befol Synthesized Via Interaction of 4-Chloro-N-(3-chloropropyl)benzamide with Morpholine". Pharmaceutical Chemistry Journal. 0091-150X. 38 (7): 381–384. doi:10.1023/B:PHAC.0000048439.38383.5f.
  4. ↑ "Eprobemide". ChemIDplus.
  5. ↑ "Befol". 4DOKTOR.RU Drug Information Handbook (به روسی). Retrieved 4 February 2014.
برگرفته از «https://fa.wikipedia.org/w/index.php?title=اپروبماید&oldid=40538797»
Pusat Layanan

UNIVERSITAS TEKNOKRAT INDONESIA | ASEAN's Best Private University
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Phone: (0721) 702022
Email: pmb@teknokrat.ac.id