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url url
  1. Weltenzyklopädie
  2. GPR39 - ویکی‌پدیا، دانشنامهٔ آزاد
GPR39 - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
GPR39
معین‌کننده‌ها
نام‌های دیگرGPR39, G protein-coupled receptor 39
شناسه‌های بیرونیOMIM: 602886 MGI: 1918361 HomoloGene: 20380 GeneCards: GPR39
موقعیت ژن (موش)
کروموزوم ۱ (موش)
کروموزومکروموزوم ۱ (موش)[۱]
کروموزوم ۱ (موش)
موقعیت ژنومی GPR39
موقعیت ژنومی GPR39
نوار1|1 E3شروع125,604,732 bp[۱]
پایان125,801,599 bp[۱]
الگوی گسترش RNA
More reference expression data
هستی‌شناسی ژن
عملکرد ملکولی• G protein-coupled receptor activity
• signal transducer activity
• metal ion binding
ترکیبات سلولی• integral component of membrane
• پوسته یاخته
• integral component of plasma membrane
• membrane
فرایند زیستی• G protein-coupled receptor signaling pathway
• GO:0072468 ورارسانی پیام
منابع: آمیگو / کوئیک‌گو
هم‌ساخت‌شناسی
گونه‌هاانسانموش
Entrez

2863

71111

آنسامبل

ENSG00000183840

ENSMUSG00000026343

یونی‌پروت

O43194

Q5U431

RefSeq (mRNA)

NM_001508

NM_027677

RefSeq (پروتئین)

NP_001499

NP_081953

موقعیت (UCSC)ن/مChr : 125.6 – 125.8 Mb
جستجوی PubMed[۲][۳]
ویکی‌داده
مشاهده/ویرایش انسانمشاهده/ویرایش موش

گیرنده ۳۹ جفت شده با پروتئین G پروتئینی است که در انسان توسط ژن GPR39 کدگذاری می‌شود.[۴][۵]

منابع

[ویرایش]
  1. ↑ ۱٫۰ ۱٫۱ ۱٫۲ GRCm38: Ensembl release 89: ENSMUSG00000026343 - Ensembl, May 2017
  2. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  3. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ McKee KK, Tan CP, Palyha OC, Liu J, Feighner SD, Hreniuk DL, Smith RG, Howard AD, Van der Ploeg LH (Mar 1998). "Cloning and characterization of two human G protein-coupled receptor genes (GPR38 and GPR39) related to the growth hormone secretagogue and neurotensin receptors". Genomics. 46 (3): 426–34. doi:10.1006/geno.1997.5069. PMID 9441746.
  5. ↑ "Entrez Gene: GPR39 G protein-coupled receptor 39".

جهت مطالعه

[ویرایش]
  • Popovics P, Stewart AJ (2011). "GPR39: A Zn2+-activated G protein-coupled receptor that regulates pancreatic, gastrointestinal and neuronal functions". Cell. Mol. Life Sci. 68 (1): 85–95. doi:10.1007/s00018-010-0517-1. PMID 20812023. S2CID 20170402.
  • Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
  • Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  • Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
  • Holst B, Holliday ND, Bach A, et al. (2005). "Common structural basis for constitutive activity of the ghrelin receptor family". J. Biol. Chem. 279 (51): 53806–17. doi:10.1074/jbc.M407676200. PMID 15383539.
  • Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
  • Hillier LW, Graves TA, Fulton RS, et al. (2005). "Generation and annotation of the DNA sequences of human chromosomes 2 and 4". Nature. 434 (7034): 724–31. Bibcode:2005Natur.434..724H. doi:10.1038/nature03466. PMID 15815621.
  • Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: Large-scale identification and characterization of putative alternative promoters of human genes". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
  • Holst B, Egerod KL, Schild E, et al. (2007). "GPR39 signaling is stimulated by zinc ions but not by obestatin". Endocrinology. 148 (1): 13–20. doi:10.1210/en.2006-0933. PMID 16959833.
  • Lauwers E, Landuyt B, Arckens L, et al. (2006). "Obestatin does not activate orphan G protein-coupled receptor GPR39". Biochem. Biophys. Res. Commun. 351 (1): 21–5. doi:10.1016/j.bbrc.2006.09.141. PMID 17054911.
  • Egerod KL, Holst B, Petersen PS, et al. (2007). "GPR39 splice variants versus antisense gene LYPD1: expression and regulation in gastrointestinal tract, endocrine pancreas, liver, and white adipose tissue". Mol. Endocrinol. 21 (7): 1685–98. doi:10.1210/me.2007-0055. PMID 17488974.
  • Yasuda S, Miyazaki T, Munechika K, et al. (2007). "Isolation of Zn2+ as an endogenous agonist of GPR39 from fetal bovine serum". J. Recept. Signal Transduct. Res. 27 (4): 235–46. doi:10.1080/10799890701506147. PMID 17885920. S2CID 33411716.
برگرفته از «https://fa.teknopedia.teknokrat.ac.id/w/index.php?title=GPR39&oldid=35260055»
رده‌ها:
  • ژن‌های روی کروموزوم انسان
  • گیرنده‌های جفت‌شونده با پروتئین جی
  • ژن‌های روی کروموزوم ۲ انسان

  • indonesia
  • Polski
  • العربية
  • Deutsch
  • English
  • Español
  • Français
  • Italiano
  • مصرى
  • Nederlands
  • 日本語
  • Português
  • Sinugboanong Binisaya
  • Svenska
  • країнська
  • Tiếng Việt
  • Winaray
  • 文
  • Русский
Sunting pranala
Pusat Layanan

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