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url url url url
  2. Weltenzyklopädie
  3. گوانابنز - ویکی‌پدیا، دانشنامهٔ آزاد
گوانابنز - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
گوانابنز
داده‌های بالینی
AHFS/Drugs.comConsumer Drug Information
مدلاین پلاسa686003
کد ATC
  • None
داده‌های فارماکوکینتیک
پیوند پروتئینی۹۰٪
نیمه‌عمر حذف۶ ساعت
شناسه‌ها
  • 2-(2,6-dichlorobenzylidene)hydrazinecarboximidamide
شمارهٔ سی‌ای‌اس
پاب‌کم CID
IUPHAR/BPS
دراگ‌بنک
کم‌اسپایدر
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.023.410 ویرایش در ویکی‌داده
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC8H8Cl2N۴
جرم مولی۲۳۱٫۰۸ g·mol−1
مدل سه بعدی (جی‌مول)
  • Clc1cccc(Cl)c1\C=N\N=C(/N)N
  • InChI=1S/C8H8Cl2N4/c9-6-2-1-3-7(10)5(6)4-13-14-8(11)12/h1-4H,(H4,11,12,14)/b13-۴+ ✔Y
  • Key:WDZVGELJXXEGPV-YIXHJXPBSA-N ✔Y
  (صحت‌سنجی)

گوانابنز (انگلیسی: Guanabenz) (با نام تجاری Wytensin) یک آگونیست آلفا گیرنده آدرنرژیک آلفا-۲ است که به عنوان یک داروی ضد فشار خون به کار می‌رود. این دارو برای درمان فشار خون بالا (فشار خون بالا) استفاده می‌شود.[۱][۲]

شایع‌ترین عوارض جانبی در طول درمان با گوانابنز سرگیجه، خواب آلودگی، خشکی دهان، سردرد و ضعف است.

گوانابنز می‌تواند باعث خواب آلودگی یا کمتر هوشیاری فرد شود، بنابراین رانندگی یا کار با ماشین‌آلات خطرناک توصیه نمی‌شود.

همچنین ببینید

منابع

  1. ↑ Walker BR, Hare LE, Deitch MW (1982). "Comparative antihypertensive effects of guanabenz and clonidine". The Journal of International Medical Research. 10 (1): 6–14. doi:10.1177/030006058201000102. PMID 7037502. S2CID 2139809.[پیوند مرده]
  2. ↑ Bonham AC, Trapani AJ, Portis LR, Brody MJ (1984). "Studies on the mechanism of the central antihypertensive effect of guanabenz and clonidine". Journal of Hypertension Supplement. 2 (3): S543-6. PMID 6599714.[پیوند مرده]
آیکون خرد

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