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url url url url
  2. Weltenzyklopädie
  3. نمونوکساسین
نمونوکساسین
از ویکی‌پدیا، دانشنامهٔ آزاد
نمونوکساسین
نام آیوپاک ارجح

7-[(3S5S)-3-Amino-5-methylpiperidin-1-yl]-1-cyclopropyl-8-methoxy-4-oxo-14-dihydroquinoline-3-carboxylic acid

شناساگرها
شماره ثبت سی‌ای‌اس 378746-64-6 N
پاب‌کم 11993740
کم‌اسپایدر 10166207
UNII P94L0PVO94
دراگ‌بانک DB06600
ChEBI CHEBI:136053
ChEMBL CHEMBL1213456
IUPHAR ligand 10836
جی‌مول-تصاویر سه بعدی Image 1

  • C[C@H]1C[C@H](N)CN(C1)c2ccc3c(c2OC)n(C4CC4)cc(c3=O)C(=O)O

  • InChI=1S/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1
    Key: AVPQPGFLVZTJOR-RYUDHWBXSA-N

    InChI=1/C20H25N3O4/c1-11-7-12(21)9-22(8-11)16-6-5-14-17(19(16)27-2)23(13-3-4-13)10-15(18(14)24)20(25)26/h5-6,10-13H,3-4,7-9,21H2,1-2H3,(H,25,26)/t11-,12-/m0/s1
    Key: AVPQPGFLVZTJOR-RYUDHWBXBZ

خصوصیات
فرمول مولکولی C20H25N3O4
جرم مولی ۳۷۱٫۴۳ g mol−1
به استثنای جایی که اشاره شده‌است در غیر این صورت، داده‌ها برای مواد به وضعیت استانداردشان داده شده‌اند (در 25 °C (۷۷ °F)، ۱۰۰ kPa)
Infobox references

نمونوکساسین (انگلیسی: Nemonoxacin) یک آنتی بیوتیک کینولون غیرفلورینه است که تحت آزمایش های بالینی قرار گرفته است.[۱]اثر آن مانند فلوئوروکینولون های دیگر است و DNA جیراز را مهار می کند و از سنتز DNA، تکثیر ژن و تقسیم سلولی جلوگیری میکند.

منابع

[ویرایش]
  1. ↑ Guo, B; Wu, X; Zhang, Y; Shi, Y; Yu, J; Cao, G; Zhang, J (2012). "Safety and clinical pharmacokinetics of nemonoxacin, a novel non-fluorinated quinolone, in healthy Chinese volunteers following single and multiple oral doses". Clinical Drug Investigation. 32 (7): 475–86. doi:10.2165/11632780-000000000-00000. PMID 22650326. S2CID 34452344.

پیوند به بیرون

[ویرایش]
در ویکی‌انبار پرونده‌هایی دربارهٔ نمونوکساسین موجود است.
آیکون خرد

این یک مقالهٔ خرد داروشناسی است. می‌توانید با گسترش آن به ویکی‌پدیا کمک کنید.

برگرفته از «https://fa.wikipedia.org/w/index.php?title=نمونوکساسین&oldid=39588609»
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