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url url url url
  2. Weltenzyklopädie
  3. برودیموپریم - ویکی‌پدیا، دانشنامهٔ آزاد
برودیموپریم - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
برودیموپریم
داده‌های بالینی
کد ATC
شناسه‌ها
  • 5-[(4-Bromo-3,5-dimethoxyphenyl)methyl]pyrimidine-2,4-diamine
شمارهٔ سی‌ای‌اس
پاب‌کم CID
کم‌اسپایدر
UNII
KEGG
ChEBI
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.054.745 ویرایش در ویکی‌داده
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC13H15BrN4O2
جرم مولی۳۳۹٫۱۹۳ g·mol−1
مدل سه بعدی (جی‌مول)
نقطه ذوب۲۲۵ تا[ابزار تبدیل: یکای ناشناخته]
  • Brc1c(OC)cc(cc1OC)Cc2cnc(nc2N)N
  • InChI=1S/C13H15BrN4O2/c1-19-9-4-7(5-10(20-2)11(9)14)3-8-6-17-13(16)18-12(8)15/h4-6H,3H2,1-2H3,(H4,15,16,17,18) ✔Y
  • Key:BFCRRLMMHNLSCP-UHFFFAOYSA-N ✔Y
  (صحت‌سنجی)

برودیموپریم(به انگلیسی: Brodimoprim) یکی از مشتقات ساختاری تری‌متوپریم است. در این ترکیب، گروه ۴-متوکسی موجود در تری‌متوپریم، با یک اتم برم جایگزین شده است.

همانند تری‌متوپریم، برودیموپریم یک مهارکننده انتخابی دی هیدروفولات ردوکتاز باکتریایی است.[۱]

منابع

  1. ↑ Thomson CJ (December 1993). "Trimethoprim and brodimoprim resistance of gram-positive and gram-negative bacteria". Journal of Chemotherapy. 5 (6): 458–64. PMID 8195838.
Pusat Layanan

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