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url url
  2. Weltenzyklopädie
  3. نشانه فرانک - ویکی‌پدیا، دانشنامهٔ آزاد
نشانه فرانک - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
آناتومی گوش طبیعی
شیارهای لاله گوش در یک بیمار ژاپنی مبتلا به آنژین صدری دیده می‌شود

نشانهٔ فرانک یک چین مورب در لاله گوش است که از تراگوس در سرتاسر لاله به لبه پشت لاله گوش کشیده می‌شود.[۱] این نشانه به نام سندرس تی. فرانک نامگذاری شده است.[۱]

فرض بر این است که نشانهٔ فرانک نشان دهنده بیماری قلبی عروقی است[۲][۳] و / یا دیابت.[۴] برخی مطالعات نشانهٔ فرانک را به عنوان نشانگر بیماری قلبی عروقی توصیف کرده اما با شدت بیماری مرتبط نیستند.[۵] در مقابل، مطالعات دیگر ارتباط بین نشانهٔ فرانک و بیماری عروق کرونر در بیماران دیابتی رد کرده‌اند.[۶] مواردی از نشانهٔ فرانک نیز در تشخیص سکته مغزی گزارش شده است. [نیازمند منبع] پیوند بین نشانهٔ فرانک و پیری زودرس و از دست دادن الیاف پوست و عروقی نیز فرض شده است.[۷] در برخی از مطالعات بر روی چین دو طرفه لاله گوش توجه شده است.[۸]

افراد شاخص با نشانهٔ فرانک [نیازمند منبع]

منابع

  1. ↑ ۱٫۰ ۱٫۱ Frank ST (August 1973). "Aural sign of coronary-artery disease". N. Engl. J. Med. 289 (6): 327–8. doi:10.1056/NEJM197308092890622. PMID 4718047.
  2. ↑ Mallinson, Tom; Brooke, David (2017). "Frank's Sign as a clinical marker of cardiovascular disease". Journal of Paramedic Practice. 9 (1): 8-10. doi:10.12968/jpar.2017.9.1.8.
  3. ↑ Miot, H.A. , Molina de Medeiros, M. etal (2006). Association between coronary artery diseaseand the diagonal earlobe an preauricular creases in men. Anais Brasileiros de Dermatologia. vol.81 no.1
  4. ↑ Mustafa Ahmed, M.D. (13 August 2014). "Earlobe Crease And Heart Disease – Fact Or Myth?". Abel Healthcare. Retrieved 8 February 2015.
  5. ↑ Lesbre JP, Castier B, Tribouilloy C, Labeille B, Isorni C (January 1987). "[Frank's sign and coronary disease]". Ann Cardiol Angeiol (Paris) (به فرانسوی). 36 (1): 37–41. PMID 3827155.
  6. ↑ Davis TM, Balme M, Jackson D, Stuccio G, Bruce DG (October 2000). "The diagonal ear lobe crease (Frank's sign) is not associated with coronary artery disease or retinopathy in type 2 diabetes: the Fremantle Diabetes Study". Aust N Z J Med. 30 (5): 573–7. doi:10.1111/j.1445-5994.2000.tb00858.x. PMID 11108067.
  7. ↑ George Griffing, M.D. (March 2014). "Frank's Sign". The New England Journal of Medicine. 370 (15). doi:10.1056/NEJMicm1213868.
  8. ↑ Evrengül H, Dursunoğlu D, Kaftan A, et al. (2004). "Bilateral diagonal earlobe crease and coronary artery disease: a significant association". Dermatology. 209 (4): 271–5. doi:10.1159/000080847. PMID 15539887.
  9. ↑ Livingston, David (November 29, 2018). "Dick Van Dyke (age 92), Premiere Of Disney's 'Mary Poppins Returns' - Arrivals". gettyimages.com. Getty Images. Retrieved November 30, 2018.
  10. ↑ تصویر نیمرخ بوش
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