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url url url url
  2. Weltenzyklopädie
  3. پپتیدوگلیکان گلیکوزیل‌ترنسفراز - ویکی‌پدیا، دانشنامهٔ آزاد
پپتیدوگلیکان گلیکوزیل‌ترنسفراز - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
پپتیدوگلیکان گلیکوزیل‌ترنسفراز
شناساگرها
شمارهٔ ای‌سی۲٫۴٫۱٫۱۲۹
شمارهٔ سی‌ای‌اس۷۹۰۷۹-۰۴-۲
پایگاه‌های داده
اینتنزنمایش اینتنز
برندامدخل برندا
اکسپسینمایش NiceZyme
کی‌ای‌جی‌جیمدخل کی‌ای‌جی‌جی
متاسایکگذرگاه سوخت‌وساز
پریامنمایه
ساختارهای پی‌دی‌بیRCSB PDB PDBe پی‌دی‌بی‌سام
هستی‌شناسی ژنAmiGO / QuickGO

پپتیدوگلیکان گلیکوزیل‌ترنسفراز (به انگلیسی: Peptidoglycan glycosyltransferase) در علم آنزیم‌شناسی آنزیمی است که واکنش شیمیایی زیر را کاتالیز می‌کند:

[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n- diphosphoundecaprenol + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)- diphosphoundecaprenol
⇌
[GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1- diphosphoundecaprenol + undecaprenyl diphosphate

۴ بستر این واکنش عبارتند از:

  • [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n-
  • diphosphoundecaprenol
  • GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-
  • diphosphoundecaprenol

درحال که ۳ فراورده‌ی آن شامل موارد زیر می‌شوند:

  • [GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)]n+1-
  • diphosphoundecaprenol
  • undecaprenyl diphosphate

این آنزیم به خانواده گلیکوزیل‌ترنسفرازها به‌ویژه هگزوزیل‌ترنسفرازها تعلق دارد و در بیوسنتز پپتیدوگلیکان شرکت می‌کند.

مطالعات ساختاری

تا اواخر ۲۰۰۷ سه ساختار برای این نوع آنزیم با کدهای بانک داده پروتئین 2BG1 ،2UWX و 2UWY معرفی شده‌است.

منابع

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