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url url url url
  2. Weltenzyklopädie
  3. لوبلین (آلکالوئید) - ویکی‌پدیا، دانشنامهٔ آزاد
لوبلین (آلکالوئید) - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
لوبلین (آلکالوئید)
داده‌های بالینی
AHFS/Drugs.comInternational Drug Names
کد ATCvet
شناسه‌ها
  • 2-((2R,6S)-6-((S)-2-Hydroxy-2-phenylethyl)-1-methylpiperidin-2-yl)-1-phenylethanone
شمارهٔ سی‌ای‌اس
پاب‌کم CID
کم‌اسپایدر
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.001.830 ویرایش در ویکی‌داده
داده‌های فیزیکی و شیمیایی
فرمول شیمیاییC22H27NO2
جرم مولی۳۳۷٫۴۶۳ g·mol−1
مدل سه بعدی (جی‌مول)
  • O=C(C[C@@H]1N([C@@H](CCC1)C[C@@H](C2=CC=CC=C2)O)C)C3=CC=CC=C3
  • InChI=1S/C22H27NO2/c1-23-19(15-21(24)17-9-4-2-5-10-17)13-8-14-20(23)16-22(25)18-11-6-3-7-12-18/h2-7,9-12,19-21,24H,8,13-16H2,1H3/t19-,20+,21-/m0/s1 N
  • Key:MXYUKLILVYORSK-HBMCJLEFSA-N N
 N✔Y (این چیست؟)  (صحت‌سنجی)

لوبلین (انگلیسی: Lobeline) دارویی است که مرکز تنفسی را تحریک می‌کند و یک آلکالوئید موجود در گیاهان یک ساله از جنس لبلیا است و به روش مصنوعی به دست می‌آید. در پزشکی از تزریق داخل وریدی یا عضلانی محلول لوبلین هیدروکلراید استفاده می‌شود.

این دارو در صورت خفگی نوزادان، مسمومیت با مواد مخدر، مونواکسید کربن و سینه‌پهلو تجویز می‌شود.[۱][۲][۳]

منابع

  1. ↑ Stead LF, Hughes JR (February 2012). "Lobeline for smoking cessation". The Cochrane Database of Systematic Reviews. 2 (2): CD000124. doi:10.1002/14651858.CD000124.pub2. PMC 7043274. PMID 22336780. On the basis of the trials which have been published in the past sixty years there is no evidence that lobeline has any long term effect on smoking cessation.
  2. ↑ Marlow SP, Stoller JK (December 2003). "Smoking cessation". Respiratory Care. 48 (12): 1238–54, discussion 1254-6. PMID 14651764.
  3. ↑ Buchhalter AR, Fant RV, Henningfield JE (2008). "Novel pharmacological approaches for treating tobacco dependence and withdrawal: current status". Drugs. 68 (8): 1067–88. doi:10.2165/00003495-200868080-00005. PMID 18484799. S2CID 46875770.

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