Technopedia Center
PMB University Brochure
Faculty of Engineering and Computer Science
S1 Informatics S1 Information Systems S1 Information Technology S1 Computer Engineering S1 Electrical Engineering S1 Civil Engineering

faculty of Economics and Business
S1 Management S1 Accountancy

Faculty of Letters and Educational Sciences
S1 English literature S1 English language education S1 Mathematics education S1 Sports Education
teknopedia

teknopedia

teknopedia

teknopedia

teknopedia

teknopedia
teknopedia
teknopedia
teknopedia
teknopedia
teknopedia
url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url url 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url url
  2. Weltenzyklopädie
  3. سیلازاپریل - ویکی‌پدیا، دانشنامهٔ آزاد
سیلازاپریل - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
سیلازاپریل
Kekulé, stereo, skeletal formula of cilazapril ((1S,9S)-9-[(2S)-2-yl]amin,-1-carbox)
نام‌گذاری آیوپاک

(1S9S)-9-[(2S)-(1-Ethoxy-1-oxo-4-phenylbutan-2-yl)amino]-10-oxo-octahydro-1H-pyridazino[12-a] [12]diazepine-1-carboxylic acid[نیازمند منبع]

شناساگرها
شماره ثبت سی‌ای‌اس ۸۸۷۶۸-۴۰-۵ N
پاب‌کم ۵۶۳۳۰, ۴۰۴۶۷۹۸۵ (1R,9S)-(2S)-butylamino isomer
کم‌اسپایدر ۵۰۸۳۱ N
UNII 8Q9454114Q N
دراگ‌بانک DB01340
KEGG D07699 ✔Y
ChEMBL CHEMBL۵۱۵۶۰۶ N
کد اِی‌تی‌سی C09AA08
جی‌مول-تصاویر سه بعدی Image 1

  • CCOC(=O)C(CCc1ccccc1)NC1CCCN2CCCC(N2C1=O)C(O)=O

  • InChI=1S/C22H31N3O5/c1-2-30-22(29)18(13-12-16-8-4-3-5-9-16)23-17-10-6-14-24-15-7-11-19(21(27)28)25(24)20(17)26/h3-5,8-9,17-19,23H,2,6-7,10-15H2,1H3,(H,۲۷٬۲۸) N
    Key: HHHKFGXWKKUNCY-UHFFFAOYSA-N N

خصوصیات
فرمول مولکولی C۲۲H۳۱N۳O۵
جرم مولی ۴۱۷٫۵ g mol−1
log P 2.212
اسیدی (pKa) 2.285
خاصیت بازی (pKb) 11.712
داروشناسی
Routes of
administration 		Oral
Legal status

POM(UK)

به استثنای جایی که اشاره شده‌است در غیر این صورت، داده‌ها برای مواد به وضعیت استانداردشان داده شده‌اند (در 25 °C (۷۷ °F)، ۱۰۰ kPa)
 N (بررسی) (چیست: ✔Y/N؟)
Infobox references

سیلازاپریل (Cilazapril) یک داروی مهارکننده آنزیم تبدیل کننده آنژیوتانسین (مهارکننده ACE) است که برای درمان فشارخون بالا و نارسایی احتقانی قلب به کار می‌رود. این دارو تحت نام‌های تجاری مختلفی ازجمله Inhibace , Vascace و Dynorm به فروش می‌رسد. این ترکیب دارای هشت ایزومر فضایی است که تنها فرم all-S دارای کاربرد پزشکی است.[۱][۲][۳]

منابع

  1. ↑ Szucs, T. (1991). "Cilazapril. A review". Drugs. 41 Suppl 1: 18–24.
  2. ↑ Jasek, W, ed. (2007). Austria-Codex (in German) (2007/2008 ed.). Vienna: Österreichischer Apothekerverlag
  3. ↑ Drugs.com: Cilazapril
Pusat Layanan

UNIVERSITAS TEKNOKRAT INDONESIA | ASEAN's Best Private University
Jl. ZA. Pagar Alam No.9 -11, Labuhan Ratu, Kec. Kedaton, Kota Bandar Lampung, Lampung 35132
Phone: (0721) 702022
Email: pmb@teknokrat.ac.id