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url url url url
  2. Weltenzyklopädie
  3. سدوهپتولوز - ویکی‌پدیا، دانشنامهٔ آزاد
سدوهپتولوز - ویکی‌پدیا، دانشنامهٔ آزاد
از ویکی‌پدیا، دانشنامهٔ آزاد
سدوهپتولوز
شناساگرها
شماره ثبت سی‌ای‌اس 3019-74-7
پاب‌کم 5459879
کم‌اسپایدر 4573620 ✔Y
MeSH sedoheptulose
ChEBI CHEBI:16802 ✔Y
جی‌مول-تصاویر سه بعدی Image 1

  • O=C([C@@H](O)[C@H](O)[C@H](O)[C@H](O)CO)CO

  • InChI=1S/C7H14O7/c8-1-3(10)5(12)7(14)6(13)4(11)2-9/h3,5-10,12-14H,1-2H2/t3-,5-,6-,7-/m1/s1 ✔Y
    Key: HSNZZMHEPUFJNZ-SHUUEZRQSA-N ✔Y

    InChI=1/C7H14O7/c8-1-3(10)5(12)7(14)6(13)4(11)2-9/h3,5-10,12-14H,1-2H2/t3-,5-,6-,7-/m1/s1
    Key: HSNZZMHEPUFJNZ-SHUUEZRQBR

خصوصیات
فرمول مولکولی C7H14O7
جرم مولی 210.182 g/mol
به استثنای جایی که اشاره شده‌است در غیر این صورت، داده‌ها برای مواد به وضعیت استانداردشان داده شده‌اند (در 25 °C (۷۷ °F)، ۱۰۰ kPa)
 ✔Y (بررسی) (چیست: ✔Y/N؟)
Infobox references

سدوهپتولوز (به انگلیسی: Sedoheptulose) با فرمول شیمیایی C7H14O7 یک ترکیب شیمیایی با شناسه پاب‌کم 5459879 است. که جرم مولی آن ۲۱۰٫۱۸۲ گرم بر مول می‌باشد.

سدوهپتولوز یک کتو هپتوز (یک مونوساکارید با هفت اتم کربن و یک گروه عاملی کتون). این ماده یکی از معدود هپتوزهای موجود در طبیعت است و در میوه‌ها و سبزیجات گوناگون از هویج و تره‌فرنگی گرفته تا انجیر و انبه و آووکادو یافت می‌شود.[۱][۲]

این ماده یک واسطه در مسیرهای تنفسی و فتوسنتز است و نقش مهمی در شاخه غیر اکسیداتیو مسیر پنتوز فسفات ایفا می‌کند.[۳][۴]

مطالعات نشان داده است که سدوهپتولوز می‌تواند نشانگرهای پیش‌التهابی را در شرایط درون‌کشتگاهی مانند اینترلوکین ۶ (IL-6) و پروتئین واکنشی سی کاهش دهد و بنابراین ممکن است بتواند التهاب سطح پایین را در انسان کاهش دهد.[۵]

افزون بر این، عدم وجود سدوهپتولوز در رژیم غذایی و هپتوزهای مرتبط با آن می‌تواند باعث ایجاد سیستینوز در هنگام نقص ژنتیکی نادر شود.[۶]

جستارهای وابسته

منابع

  1. ↑ Ogata, James N.; Kawano, Yoshihiko; Bevenue, Arthur; Casarett, Louis J. (January 1972). "Ketoheptose content of some tropical fruits". Journal of Agricultural and Food Chemistry. 20 (1): 113–115. doi:10.1021/jf60179a011.
  2. ↑ Okuda, Takuo; Mori, Kazuko (June 1974). "Distribution of manno-heptulose and sedoheptulose in plants". Phytochemistry. 13 (6): 961–964. doi:10.1016/S0031-9422(00)91430-4.
  3. ↑ Horecker, B. L; Smyrniotis, P. Z (1953). "Transaldolase: The Formation of Fructose-6-Phosphate from Sedoheptulose-7-Phosphate". Journal of the American Chemical Society. 75 (8): 2021. doi:10.1021/ja01104a532.
  4. ↑ Patra, Krushna C; Hay, Nissim (2014). "The pentose phosphate pathway and cancer". Trends in Biochemical Sciences. 39 (8): 347. doi:10.1016/j.tibs.2014.06.005. PMC 4329227. PMID 25037503.
  5. ↑ Park, Chan Hum; Tanaka, Takashi; Yokozawa, Takako (September 2013). "Evaluation of 7-O-galloyl-d-sedoheptulose, isolated from Corni Fructus, in the adipose tissue of type 2 diabetic db/db mice". Fitoterapia. 89: 131–142. doi:10.1016/j.fitote.2013.03.026. ISSN 0367-326X. PMID 23567861.
  6. ↑ Kardon, Tamas; Stroobant, Vincent; Veiga-da-Cunha, Maria; Schaftingen, Emile Van (15 October 2008). "Characterization of mammalian sedoheptulokinase and mechanism of formation of erythritol in sedoheptulokinase deficiency". FEBS Letters. 582 (23–24): 3330–3334. doi:10.1016/j.febslet.2008.08.024. PMID 18775706.
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